We want to hear from you!

We want to continually improve our application. Your feedback is invaluable in helping us create a better user experience. Please take a few minutes to share your impressions and suggestions with us.

    Name

    Email

    Rating

    Your feedback

    Endometriosis risk factors

    Endometriosis is a multifactorial disease with various contributing factors and development theories. Key risk factors include early menarche, short menstrual cycles, and prolonged menses, which double the risk. Social changes like earlier menarche and delayed childbirth increase menstrual cycles and estrogen exposure, elevating disease risk. Genetics, epigenetic factors, and stem cells also play roles. Protective factors include parity, oral contraceptives, regular exercise, and breastfeeding. Lifestyle choices, such as diet and avoiding red meat and trans fats, impact risk. Clinicians should identify at-risk teens through careful history taking, especially those with severe dysmenorrhea and family history.

    Read more

    Gynecological symptoms

    Endometriosis is a chronic inflammatory condition with a wide variety of symptoms that can present differently in adolescents compared to adults. These symptoms can include dysmenorrhea (painful menstruation), non-menstrual pelvic pain, pain during or after sexual intercourse (deep dyspareunia), and heavy menstrual bleeding. Recognizing these symptoms in adolescents can be challenging, as they may be considered as classic menstrual pain. It is important to not overlook persisting symptoms, especially if they do not improve with first-line treatment. The pathophysiology of pelvic pain in endometriosis involves complex mechanisms both in the peripheral and central nervous systems.

    Read more

    Non-gynecological symptoms

    Adolescents with endometriosis can present non-gynecological symptoms. Common symptoms include gastrointestinal issues like altered bowel movement, dyschezia, colic rectal pain, bloating and nausea. Urinary symptoms such as painful urination, recurrent urinary tract infections, urgency, and blood in urine can also be present. Diaphragmatic involvement may cause chest and shoulder pain while neural involvement may be responsible for cramps, paresthesia and sciatic pain. Adolescents often experience chronic fatigue, headaches, dizziness, and insomnia. Co-existing conditions like migraines, irritable bowel syndrome, and fibromyalgia further complicate the diagnosis and worsen pain sensitivity.

    Read more

    Symptoms and psychosocial impact of endometriosis

    Endometriosis presents significant diagnostic challenges, with delays of 6-12 years due to non-specific symptoms. Adolescents often suffer from severe dysmenorrhea, chronic pelvic pain, dyspareunia, and gastrointestinal issues. Secondary dysmenorrhea is frequently linked to endometriosis, requiring thorough evaluation. Symptoms like chronic fatigue, migraines, and urinary problems are common.

    The disease profoundly impacts work, school, relationships, and mental health, with sufferers losing an average of five workdays per month. Affecting millions globally, endometriosis incurs substantial economic costs due to treatment and absenteeism, highlighting its significant socio-psychological burden.

    Read more

    Socio-psychological impact

    Endometriosis has profound social and economic consequences, with significant direct and indirect costs. Direct costs, including medical treatments and surgeries, range from $1,100 to $12,100 per patient annually. Indirect costs, primarily from absenteeism, are around $3,000 per year. Beyond economic impact, endometriosis severely affects adolescents’ quality of life, causing psychological distress, anxiety, depression, and impaired daily functioning.

    It disrupts education and social activities and the stigma surrounding the condition can lead to minimization of symptoms by peers, families and healthcare professionals. The condition also affects sexual health and young women may fear their fertility could be compromized, further decreasing emotional well-being.

    Read more